Systematic review and meta-analysis of colon cleansing preparations in patients with inflammatory bowel disease


No.	Divisions/Titles for Abstract	Details
1	Citation	Out of 439 citations, 4 trials fulfilled our inclusion criteria (n = 449 patients). One trial assessed the impact of adding simethicone to polyethylene glycol (PEG) 4 L with no effect on bowel cleansing quality, but a better tolerance. Another trial compared senna to castor oil, again without any differences in term of bowel cleansing. Two trials compared the efficacy of PEG high-volume vs PEG low-volume associated to an adjuvant in split-dose regimens: PEG low-dose efficacy was not different to PEG high-dose; OR = 0.84 (0.37-1.92)
2	Abstract Title	Systematic review and meta-analysis of colon cleansing preparations in patients with inflammatory bowel disease
3	Abstract Source	World J Gastroenterol. 2017 Aug 28; 23(32): 5994–6002.
4	Abstract Author(s)	Sophie Restellini, Omar Kherad, Talat Bessissow, Charles Ménard, Myriam Martel, Maryam Taheri Tanjani, Peter L Lakatos, and Alan N Barkun
5	Article Affiliation	PMC PubMed Central
6	Abstract	To performed a systematic review and meta-analysis to determine any possible differences in terms of effectiveness, safety and tolerability between existing colon-cleansing products in patients with inflammatory bowel disease.
7	Summary	In inflammatory bowel disease population, PEG low-volume regimen seems not inferior to PEG high-volume to clean the colon, and yields improved willingness-to-repeat. Further additional research is urgently required to compare contemporary products in this population.
8	Article Published Date	2017
9	Link	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583585/